The Nikon Z6 is a full-frame mirrorless camera, while the Nikon D500 is a DX-format (APS-C) DSLR built with sports and wildlife in mind. Choose the Z6 for low-light work, video and a modern mirrorless workflow; choose the D500 if you want a tough, action-focused DSLR with extra telephoto reach from its smaller sensor. Confirm exact specs on Nikon’s pages, since both are older models now.

What each camera is for
The Z6 is an all-round full-frame body. It suits portraits, landscapes, events, travel and video, and it offers an electronic viewfinder that shows exposure before you shoot.
The D500 was Nikon’s flagship DX camera. It is known for fast continuous shooting, a wide autofocus coverage area and a rugged body, which made it popular for birds, sport and other fast subjects.
Key differences to weigh
- Sensor format: full-frame usually gives a shallower depth of field and better results in dim light. DX crops the view, which effectively adds reach to telephoto lenses.
- Viewfinder: the D500 has an optical viewfinder with no lag. The Z6 has an electronic one that shows your settings before the shot.
- Lenses: the D500 uses the F mount, with a huge range of new and used lenses. The Z6 uses the Z mount, and can use F-mount lenses through Nikon’s adapter, though features can vary by lens.
- Video: the Z6 is generally the more comfortable video camera thanks to its mirrorless design.
- Size and weight: both are substantial, but the D500 body is chunkier, while the Z6 pairs well with the smaller Z lenses.
Age is worth keeping in mind too. Both cameras are no longer new, so many buyers look at used examples. If you go that route, check the shutter count where relevant, inspect the body and mount for wear, and buy from a seller who offers a return option.
Quick comparison
| Trait | Z6 | D500 |
|---|---|---|
| Type | Mirrorless | DSLR |
| Sensor format | Full-frame | DX (APS-C) |
| Viewfinder | Electronic | Optical |
| Lens mount | Z | F |
How to decide
- Pick your main subject. Fast wildlife and sport lean toward the D500; mixed shooting leans toward the Z6.
- Look at the lenses you already own. If you have F-mount telephotos, the D500 may fit with no extra purchases.
- Consider the future. Nikon’s current development focuses on the Z mount.
- Think about video. If you record often, the Z6 is the easier route.
FAQ
Can I use D500 lenses on the Z6?
Many F-mount lenses work through Nikon’s FTZ adapter, although autofocus support depends on the lens. Check the compatibility list before buying.
Does the D500’s crop factor make it better for wildlife?
The smaller sensor gives extra reach with the same lens, which helps with distant subjects. A full-frame body can still match this by cropping, though with fewer pixels on the subject.
The Short Version
The Z6 is the flexible full-frame mirrorless option, and the D500 is the focused, rugged DX DSLR for action. Choose according to your subjects and lenses, and confirm details on Nikon’s pages.