The Nikon D780 is a full frame DSLR that combines an optical viewfinder with strong live view and video, while the D500 is a crop sensor camera built for fast action and reach. Choose the D780 for all round work and low light, and the D500 for wildlife and sports.

What Each Camera Is For
The D780 is a versatile full frame body that suits portraits, events, travel and video. The D500 is a DX flagship style camera designed for speed, with a large autofocus system and a rugged build. Both use the Nikon F mount, so the same lenses fit.
Key Differences
| Area | Nikon D780 | Nikon D500 |
|---|---|---|
| Sensor | Full frame (FX) | Crop (DX) |
| Strength | Image quality, video, live view | Burst speed, focus coverage |
| Live view focus | Strong, sensor based | More limited |
| Reach | Standard | Extended by the crop factor |
| Body | All round DSLR | Tough action body |
Check exact burst rates, point counts and card types on Nikon’s pages.
Viewfinder Versus Live View
Through the viewfinder both cameras use a traditional DSLR focusing system, and the D500 spreads its points across a wider part of the frame, which helps with off center subjects. In live view, the D780 behaves much like a mirrorless camera, with focus across much of the frame and eye detection that helps with portraits and video.
Low Light and Image Quality
A full frame sensor generally gathers more light and offers shallower depth of field, which many portrait shooters want. The D500 does well for its sensor size, but if you often shoot in dim rooms, the D780 will have the edge.
How to Decide
- Name your main subject type: distant and fast leans toward the D500, people and scenes lean toward the D780.
- Think about video. The D780 is stronger here.
- Consider lens reach. A crop body stretches telephoto lenses further.
- Handle both for weight and grip comfort.
Some photographers own both: the D500 for telephoto days and the D780 for people, interiors and video. Because they share the F mount, lenses move freely between them. A 70-200mm zoom, for example, gives a classic portrait range on the D780 and a longer, tighter view on the D500, so a single lens does double duty. If you can only afford one body now, name the subject you photograph most often and let that decide.
FAQ
Can the D780 shoot wildlife?
Yes, but a crop body gives more reach and a faster burst, so the D500 is usually easier for small, distant subjects.
Are DX lenses usable on the D780?
They mount, but a cropped mode lowers resolution. Full frame lenses are the better match.
The Short Version
Choose the D780 for full frame quality, live view and video. Choose the D500 for reach, speed and wide focus coverage. Confirm the details on the maker’s page.